• Fares Azoury, Steve Heymann, Catalina Acevedo, Marc Spielmann, Philippe Vielh, Jean-Rémi Garbay, Alphonse G Taghian, Hugo Marsiglia, and Céline Bourgier.
• Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
• Radiother Oncol. 2012 May 1; 103 (2): 193-8.

IntroductionThe present study prospectively reported both physicians' and patients' assessment for toxicities, cosmetic assessment and patients' satisfaction after 3D-conformal accelerated partial breast irradiation (APBI).Materials And MethodsFrom October 2007 to September 2009, 30 early breast cancer patients were enrolled in a 3D-conformal APBI Phase II trial (40 Gy/10 fractions/5 days). Treatment related toxicities and cosmetic results were assessed by both patients and physicians at each visit (at 1, 2, 6 months, and then every 6 months). Patient satisfaction was also scored.ResultsAfter a median follow-up of 27.7 months, all patients were satisfied with APBI treatment, regardless of cosmetic results or late adverse events. Good/excellent cosmetic results were noticed by 80% of patients versus 92% of cases by radiation oncologists. Breast pain was systematically underestimated by physicians (8-20% vs. 16.6-26.2%; Kappa coefficient KC=0.16-0.44). Grade 1 and 2 fibrosis and/or breast retraction occurred in 7-12% of patients and were overestimated by patients (KC=0.14-0.27).ConclusionsPresent results have shown discrepancies between patient and physician assessments. In addition to the assessment of efficacy and toxicity after 3D-conformal APBI, patients' cosmetic results consideration and satisfaction should be also evaluated.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

13 keywords...

hide…