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- B Dreno, P Celerier, and P Litoux.
- Department of Dermatology, Hôtel Dieu, Nantes, France.
- Acta Haematol. 1993 Jan 1; 89 Suppl 1: 28-32.
AbstractIn cutaneous T-cell lymphomas (CTCL; mycosis fungoides and Sézary syndrome), the standard therapies tend to be effective but not curative. Single drug therapy with either interferon-alpha or retinoids shows a response rate of about 45%. In this article, we report the results obtained in the treatment of CTCL with a combined therapy. To date, four clinical studies have been carried out using a combination of low doses of interferon-alpha and retinoids for treatment in the early stages of CTCL. The mechanism of action of this combination therapy is unknown.
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