• Immunobiology · Mar 2021

    Review

    What do we know about the antibody responses to SARS-CoV-2?

    • Francisco Alejandro Lagunas-Rangel and Venice Chávez-Valencia.
    • Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), Mexico City, Mexico. Electronic address: francisco.lagunas@cinvestav.mx.
    • Immunobiology. 2021 Mar 1; 226 (2): 152054.

    AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of the adaptive immune response, to develop vaccines and therapies, we must understand the antibody response to SARS-CoV-2 infection. In this work, we summarize the most important findings of antibody-mediated immunity against SARS-CoV-2 and highlight its role in the efficient use of plasma from convalescent patients and the direct application of antibodies as treatment.Copyright © 2021 Elsevier GmbH. All rights reserved.

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