• Anne-Elie Carsin, Elaine Fuertes, Emmanuel Schaffner, Debbie Jarvis, Josep M Antó, Joachim Heinrich, Valeria Bellisario, Cecilie Svanes, Dirk Keidel, Medea Imboden, Joost Weyler, Dennis Nowak, Jesus Martinez-Moratalla, José-Antonio Gullón, José Luis Sanchez Ramos, Seraina Caviezel, Anna Beckmeyer-Borowko, Chantal Raherison, Isabelle Pin, Pascal Demoly, Isa Cerveri, Simone Accordini, Thorarinn Gislason, Kjell Toren, Bertil Forsberg, Christer Janson, Rain Jogi, Margareta Emtner, Gómez RealFranciscoFDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway., Wasif Raza, Bénédicte Leynaert, Silvia Pascual, Stefano Guerra, Shyamali C Dharmage, Nicole Probst-Hensch, and Judith Garcia-Aymerich.
• ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; IMIM (Hospital del Mar Medical Research Institute), Spain.
• Respir Med. 2019 Jan 1; 146: 116-123.

IntroductionRestrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with normal spirometry.MethodsRestrictive spirometry pattern was defined as a having post-bronchodilator FEV1/FVC ≥ Lower Limit of Normal and a FVC<80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physical activity was measured using the International Physical Activity Questionnaire. The odds of having low physical activity (<1st study-specific tertile) was evaluated using adjusted logistic regression models.ResultsSubjects with a restrictive spirometry pattern (n = 280/4721 in ECRHS, n = 143/3570 in SAPALDIA) reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET·min/week in ECRHS, and 3519 vs 3945 MET·min/week in SAPALDIA). Subjects with a restrictive spirometry pattern were more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95%CI 1.07-1.86]) than those with a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levels did not fully explain this finding.ConclusionAdults with a restrictive spirometry pattern were more likely to report low levels of physical activity than those with normal spirometry. These results highlight the need to identify and act on this understudied but prevalent condition.Copyright © 2018 Elsevier Ltd. All rights reserved.

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