• Xiangjun Wu, Hui Hui, Meng Niu, Liang Li, Li Wang, Bingxi He, Xin Yang, Li Li, Hongjun Li, Jie Tian, and Yunfei Zha.
• School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, 100190, China; CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Institute of Automation, Beijing, 100190, China.
• Eur J Radiol. 2020 Jul 1; 128: 109041.

PurposeTo develop a deep learning-based method to assist radiologists to fast and accurately identify patients with COVID-19 by CT images.MethodsWe retrospectively collected chest CT images of 495 patients from three hospitals in China. 495 datasets were randomly divided into 395 cases (80%, 294 of COVID-19, 101 of other pneumonia) of the training set, 50 cases (10%, 37 of COVID-19, 13 of other pneumonia) of the validation set and 50 cases (10%, 37 of COVID-19, 13 of other pneumonia) of the testing set. We trained a multi-view fusion model using deep learning network to screen patients with COVID-19 using CT images with the maximum lung regions in axial, coronal and sagittal views. The performance of the proposed model was evaluated by both the validation and testing sets.ResultsThe multi-view deep learning fusion model achieved the area under the receiver-operating characteristics curve (AUC) of 0.732, accuracy of 0.700, sensitivity of 0.730 and specificity of 0.615 in validation set. In the testing set, we can achieve AUC, accuracy, sensitivity and specificity of 0.819, 0.760, 0.811 and 0.615 respectively.ConclusionsBased on deep learning method, the proposed diagnosis model trained on multi-view images of chest CT images showed great potential to improve the efficacy of diagnosis and mitigate the heavy workload of radiologists for the initial screening of COVID-19 pneumonia.Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

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