• Alzheimers Dement · Oct 2014

    Florbetapir (18F) for brain amyloid positron emission tomography: highlights on the European marketing approval.

    • Anabel Cortes-Blanco, Concha Prieto-Yerro, Raul Martinez-Lazaro, Javier Zamora, Adolfo Jiménez-Huete, Marion Haberkamp, Johannes Pohly, Harald Enzmann, Jörg Zinserling, Valerie Strassmann, and Karl Broich.
    • Pharmacology and Clinical Evaluation Division, Agencia Española de Medicamentos y Productos Sanitarios, Madrid, Spain. Electronic address: acortesb_autonomo@aemps.es.
    • Alzheimers Dement. 2014 Oct 1; 10 (5 Suppl): S395-9.

    AbstractFlorbetapir (18F) for brain amyloid positron emission tomography (PET) imaging has been recently approved in Europe to estimate β-amyloid neuritic plaque density in the brain when the subject is still alive. Such density is one of the key issues for the definitive diagnosis of Alzheimer's disease (AD) at autopsy. This capability of florbetapir (18F) is regarded as a significant improvement in the diagnostic procedures for adult patients with cognitive impairment who are being evaluated for AD and other causes of cognitive impairment. The current paper highlights the specific characteristics of the European marketing authorization of florbetapir (18F).Copyright © 2014 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

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