• Mt. Sinai J. Med. · Sep 1998

    Case Reports

    Severe hyponatremia, neuroleptic malignant syndrome, rhabdomyolysis and acute renal failure: a case report.

    • C Elizalde-Sciavolino, A Racco, T Proscia-Lieto, and M Kleiner.
    • Department of Medicine, Staten Island University Hospital, NY, USA.
    • Mt. Sinai J. Med. 1998 Sep 1; 65 (4): 284-8.

    AbstractAcute renal failure secondary to myoglobinuria is a rare yet possible complication of malignant neuroleptic syndrome associated with the use of dopamine antagonists. We describe the case of a 42-year-old schizophrenic man who presented with severe hyponatremia, and proceeded to acute malignant neuroleptic syndrome, rhabdomyolysis, and acute renal failure. We contend that the acute hyponatremia may have served as a precipitating factor.

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