• Blood Transfus · May 2020

    Practice Guideline

    Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.

    • Patrizia Accorsi, Pierluigi Berti, Vincenzo de Angelis, Giustina De Silvestro, Luca Mascaretti, Angelo Ostuni, and Italian Society for Transfusion Medicine and Immunohaematology (SIMTI) and the Italian Society for Haemapheresis and Cell Manipulation (SIdEM).
    • Department of Haematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy.
    • Blood Transfus. 2020 May 1; 18 (3): 163-166.

    AbstractPassive immunotherapy with plasma derived from convalescent patients recovering from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that blood establishments are ready to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution, and control of product use. This Position paper aims to give recommendations on the biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.

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