• Clinics in perinatology · Sep 2019

    Review

    Nasal Intermittent Mandatory Ventilation Versus Nasal Continuous Positive Airway Pressure Before and After Invasive Ventilatory Support.

    • Osayame Ekhaguere, Shama Patel, and Haresh Kirpalani.
    • Department of Pediatrics, Section of Neonatal-Perinatal Medicine, Indiana University, Riley Hospital for Children at Indiana University Health, 1030 West Michigan Street, C4600, Indianapolis, IN 46202, USA. Electronic address: osaekhag@iu.edu.
    • Clin Perinatol. 2019 Sep 1; 46 (3): 517-536.

    AbstractContinuous positive airway pressure (CPAP), noninvasive intermittent positive pressure ventilation (NIPPV), and heated humidified high-flow nasal cannula (HHFNC) are modes of noninvasive respiratory support used in neonatal practice. These modes of noninvasive respiratory support may obviate mechanical ventilation, prevent extubation failure, and reduce the risk of developing bronchopulmonary dysplasia. Although the physiologic bases of CPAP and HHFNC are well delineated, and their modes and practical application consistent, those of NIPPV are unproven and varied. Available evidence suggests that NIPPV is superior to CPAP as a primary and postextubation respiratory support in preterm infants.Copyright © 2019 Elsevier Inc. All rights reserved.

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