• Helv Paediatr Acta · Aug 1988

    Case Reports

    Unusual evolution of Wilms tumor in a patient with Wiedemann-Beckwith syndrome.

    • C Rey, A del Molino, F Santos, S Malaga, and M Crespo.
    • Department of Pediatrics, N.S. Covadonga Hospital, Asturias, Spain.
    • Helv Paediatr Acta. 1988 Aug 1; 43 (1-2): 91-6.

    AbstractA very unusual case of Wilms tumor in a child with Wiedemann-Beckwith syndrome is presented. The patient had his first metastasis after a disease-free interval longer than three years. Later, he developed spinal epidural involvement. Both data emphasize the oncogenic potential of Wiedemann-Beckwith syndrome in children and support the contention that Wiedemann-Beckwith syndrome worsens the prognosis of Wilms tumor. Patients with Wilms tumor associated to Wiedemann-Beckwith syndrome should receive intensive therapy as well as close and prolonged follow-up in spite of apparent tumor remission.

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