• Internal medicine · Jun 2021

    Case Reports

    Severe Measles Encephalitis and Acute Disseminated Encephalomyelitis in an Immunocompetent Japanese Young Male.

    • Yoshikazu Mutoh, Yuya Kano, Takuya Oguri, Hideki Kato, Takumi Umemura, Chihiro Norizuki, Toshihiko Ichihara, and Hiroyuki Yuasa.
    • Department of Infectious Diseases, Tosei General Hospital, Japan.
    • Intern. Med. 2021 Jun 15; 60 (12): 1971-1976.

    AbstractMeasles encephalitis rarely affects young adults and has no established treatment strategy. This brief report described the rare case of an immunocompetent 30-year-old man with severe measles pneumonia and encephalitis, following the autoimmune disease acute disseminated encephalomyelitis, during a large measles outbreak in 2018 in Japan. With multidisciplinary treatments, including corticosteroids, intravenous immunoglobulins, vitamin A, and therapeutic plasma exchange, the patient was successfully treated. This case provides a new strategy for treating measles encephalitis and its complications during measles outbreak.

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