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Int J Gynaecol Obstet · Jan 1995
Randomized Controlled Trial Comparative Study Clinical TrialOxytocin induction of labor: a comparison of 20- and 60-min dose increment levels.
- S Goni, H Sawhney, and S Gopalan.
- Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
- Int J Gynaecol Obstet. 1995 Jan 1; 48 (1): 31-6.
ObjectivesTo compare the efficacy and complications of oxytocin dose increments at 20- and 60-min intervals for induction of labor in women with low parity.MethodsOne hundred women of low parity requiring induction of labor were randomly allocated to 20- and 60-min oxytocin dose increments, 50 patients in each group. The basal oxytocin dose was 1 milliunit/min and doubling of the oxytocin dose was done at intervals of 20 and 60 min.ResultsThe group with 60-min increments had a decreased incidence of uterine hyperstimulation, cesarean section and operative vaginal delivery. The induction-delivery interval was similar in both groups.ConclusionThe oxytocin infusion regimen with increments at 60-min intervals is safer than and equally effective as 20-min incremental intervals.
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