• Int. J. Tuberc. Lung Dis. · Oct 1999

    Health status, dyspnea, lung function and exercise capacity in patients with chronic obstructive pulmonary disease.

    • K Stavem, J Boe, and J Erikssen.
    • HELTEF Foundation for Health Services Research, Nordbyhagen, Norway. knut.stavem@klinmed.uio.no
    • Int. J. Tuberc. Lung Dis. 1999 Oct 1; 3 (10): 920-6.

    SettingA secondary hospital outside Oslo.ObjectiveTo assess relationships between health status and measures of dyspnea, lung function and exercise capacity in patients with chronic obstructive pulmonary disease (COPD), to identify dimensions where lung-specific instruments associate and discriminate better than general measures.DesignWe assessed health status in 59 out-patients with COPD, using the following instruments: Short Form 36 (SF-36)-a general health status measure, Respiratory Quality of Life Questionnaire (RQLQ)-a lung-specific measure, the Karnofsky performance scale, and a rating scale. All patients rated their dyspnea and had spirometry and exercise capacity measured.ResultsMean (SD) patient age was 57.3 (9.7) years, FEV1 47% (15%) of predicted, 6 minute walk distance 503 m (122 m). Dyspnea was the strongest predictor for health status. Both SF-36 and RQLQ had dimensions associating well with dyspnea and exercise capacity. The associations with FEV1 ranged from none to moderate.ConclusionAll RQLQ scales had a moderate to substantial association with indices of dyspnea and exercise capacity, while the SF-36 associated well only in dimensions related to physical health. The general measure has a broader scope and complements the lung-specific measure. These findings support the construct validity of both the SF-36 and the RQLQ, and justify using a general measure to supplement a lung-specific measure.

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