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Monaldi Arch Chest Dis · Dec 2020
Distinct phenotypes in COVID-19 may require distinct pulmonary rehabilitation strategies.
- Eduardo Eriko Tenório De França, Ubirace Elihimas Junior, Paulo Adriano Schwingel, CarvalhoCelso R FCRFDepartment of Physical Therapy, University of São Paulo, São Paulo. cscarval@usp.br., and Brasileiro-SantosMaria do SocorroMDSDepartment of Physiotherapy and Postgraduate Program in Physiotherapy, Federal University of Paraiba, João Pessoa. sbrasileiro@yahoo.com.br..
- Department of Physiotherapy and Postgraduate Program in Physiotherapy, Federal University of Paraiba, João Pessoa. edueriko@hotmail.com.
- Monaldi Arch Chest Dis. 2020 Dec 3; 90 (4).
AbstractThe novel coronavirus (SARS-CoV-2) has distinct clinical manifestations that can vary from an asymptomatic condition to severe acute respiratory failure. Phenotypes are attributable to different pathophysiological mechanisms and require different treatment strategies. The assessment and identification of different phenotypes can guide therapy configurations such as oxygen therapy, non-invasive ventilation, airway management, and tracheal intubation. Further studies are essential to provide information on the influence of phenotypes in the decision of rehabilitation strategies. The sequelae left in the respiratory system of COVID-19 survivors and its limitations will be a challenge for rehabilitation services worldwide. Lung injuries are directly related to the phenotypes presented, and depending on the degree of these injuries, rehabilitation strategies can be targeted. We believe that differentiating patients, according to their respective phenotypes, can improve decision-making in treatment and individualized rehabilitation.
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