• Arch Phys Med Rehabil · Dec 2018

    Randomized Controlled Trial

    Automated Mechanical Peripheral Stimulation Effects on Gait Variability in Individuals With Parkinson Disease and Freezing of Gait: A Double-Blind, Randomized Controlled Trial.

    • KleinerAna Francisca RozinAFRPolitecnico di Milano, Department of Electronics, Information, and Bioengineering, Milan, Italy; University Center of Anápolis, Uni Evangélica, Anápolis, Goiás, Brazil. Electronic address: anafrkleiner@gmail.com., Souza PagnussatAlineAMovement Analysis and Neurological Rehabilitation Laboratory, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Brazil; Rehabilitation Sciences Graduate Program, Universidade Federal de Ciências da Saúde de Porto Ale, Camila Pinto, Redivo MarcheseRitcheleRMovement Analysis and Neurological Rehabilitation Laboratory, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Brazil., Ana Paula Salazar, and Manuela Galli.
    • Politecnico di Milano, Department of Electronics, Information, and Bioengineering, Milan, Italy; University Center of Anápolis, Uni Evangélica, Anápolis, Goiás, Brazil. Electronic address: anafrkleiner@gmail.com.
    • Arch Phys Med Rehabil. 2018 Dec 1; 99 (12): 2420-2429.

    ObjectiveTo assess the effects of automated peripheral stimulation (AMPS) in reducing gait variability of subjects with Parkinson disease (PD) and freezing of gait (FOG) treated with AMPS and to explore the effects of this treatment on gait during a single task (walking) and a dual task (walking while attending the word-color Stroop test).DesignInterventional, double-blinded, placebo-controlled, randomized trial.SettingClinical rehabilitation.ParticipantsThirty subjects were randomized into 2 groups: AMPS (n=15) and AMPS sham (n=15).InterventionsBoth groups received 2 treatment sessions a week for 4 consecutive weeks (totaling 8 treatment sessions). AMPS was applied by using a medical device (Gondola™) and consisted in mechanical pressure stimulations delivered by metallic actuators on 4 areas of the feet. Treatment parameters and device configuration were modified for AMPS sham group.Main Outcome MeasuresGait analyses were measured at baseline and after the first, fourth, and eighth treatment sessions.ResultsInteractions among groups and sessions were found for both conditions while off anti-Parkinsonian medications. AMPS decreased gait variability in subjects with PD and FOG for both single and dual task conditions.ConclusionsAMPS is an effective add-on therapy for treating gait variability in patients with PD and FOG.Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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