• J Natl Compr Canc Netw · Jan 2014

    Case Reports

    Brentuximab vedotin in patients with relapsed HIV-related lymphoma.

    • Mitul Gandhi and Adam Petrich.
    • From Northwestern University Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, Department of Internal Medicine, Division of Hematology & Oncology, Chicago, Illinois.
    • J Natl Compr Canc Netw. 2014 Jan 1; 12 (1): 16-9; quiz 19.

    AbstractLymphoma is a well-recognized complication in patients infected with HIV. Although its incidence has declined since the advent of antiretroviral therapy, it remains higher than seen in the general population. Several recent studies have noted improvement in clinical outcomes with the use of modern chemoimmunotherapy regimens. In patients who experience relapse, however, fewer data are available on the role of immunotherapy and its impact on outcomes. This case report presents 2 patients with relapsed HIV-associated lymphoma who experienced a second complete remission after treatment with the immunotherapy agent brentuximab vedotin.

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