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Randomized Controlled Trial Multicenter Study
Nissen fundoplication in children with and without neurological impairment: A prospective cohort study.
- Charlotte K Knatten, Morten Kvello, Thomas J Fyhn, Bjørn Edwin, Ole Schistad, Lars Aabakken, Are H Pripp, Heidi Kjosbakken, Ragnhild Emblem, and Kristin Bjørnland.
- Institute of Clinical Medicine, University of Oslo, Norway; Department of Gastrointestinal and Pediatric surgery, Oslo University Hospital, Rikshospitalet, Norway. Electronic address: charlotte@knatten.org.
- J. Pediatr. Surg. 2016 Jul 1; 51 (7): 1115-21.
BackgroundIt is assumed that children with neurological impairment (NI) have inferior results after fundoplication compared to those without NI (non-NI). The aim of this study was to assess outcome after fundoplication in children with and without NI.Methods87/105 patients (46 NI, 41 non-NI) undergoing fundoplication between 2003 and 2009 were included in this prospective two-center cohort study. Complications occurring within the first 30days were scored from 0 to 100 by the comprehensive complication index (CCI). Follow-up included clinical examination, upper gastrointestinal contrast study and 24-h pH monitoring 6months postoperatively, then phone-interviews 1, 2 and 4years later.ResultsThere were no statistical differences in age (NI 3.1 years [0.2-15.2] vs non-NI 5.0 years [0.4-15], p=.14) or in total CCI score (NI 20.9 [0-44.9] vs non-NI 8.7 [0-40.6], p=.57). Hospital stay was longer for NI children (9days [4-57] vs non-NI: 4days [2-16], p<0.001). More than 90% of parents in both groups reported that the fundoplication had improved the child's overall condition. Recurrence of gastroesophageal reflux disease (GERD) was diagnosed in 12 NI and 7 non-NI patients (p=.31).ConclusionsEarly complications, GERD recurrence, and long-term parental satisfaction after fundoplication did not differ between NI and non-NI patients.Copyright © 2016 Elsevier Inc. All rights reserved.
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