• Elizabet Méndez-Eirín, Xacobe Flores-Ríos, Fernando García-López, Alberto J Pérez-Pérez, Rodrigo Estévez-Loureiro, Pablo Piñón-Esteban, Guillermo Aldama-López, Jorge Salgado-Fernández, Ramón A Calviño-Santos, José M Vázquez Rodríguez, Nicolás Vázquez-González, and Alfonso Castro-Beiras.
• Unidad de Hemodinámica, Servicio de Cardiología, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
• Rev Esp Cardiol (Engl Ed). 2012 Mar 1; 65 (3): 227-33.

Introduction And ObjectivesWe sought to compare the predictive value of the Thrombolysis In Myocardial Infarction (TIMI), Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC), Primary Angioplasty in Myocardial Infarction (PAMI), and Global Registry for Acute Coronary Events (GRACE) scores for the outcome of ST-segment elevation acute coronary syndrome undergoing urgent percutaneous coronary intervention.MethodsWe performed a retrospective analysis of a cohort composed of all consecutive patients with ST-segment elevation acute coronary syndrome treated by urgent percutaneous coronary intervention between 2006 and 2010 (n=1503). TIMI, PAMI, CADILLAC, and GRACE risk scores were calculated for each patient according to different clinical variables. We assessed the predictive accuracy of these scores for death, reinfarction, and target-vessel revascularization at 30 days and 1 year, using the C statistic, which was obtained by means of logistic regression and ROC curves.ResultsThe TIMI, PAMI, CADILLAC and GRACE showed an excellent predictive value for 30-day and 1-year mortality (C statistic range, 0.8-0.9), with superiority of the TIMI, CADILLAC, and GRACE risk models. The performance of these 4 scores was poor for both reinfarction and target-vessel revascularization (C statistic, 0.5-0.6).ConclusionsThe TIMI, PAMI, CADILLAC, and GRACE scores provide excellent information to stratify the risk of mortality in patients treated by percutaneous coronary intervention. The TIMI, CADILLAC, and GRACE models have higher predictive accuracy. The usefulness of these models for reinfarction and target-vessel revascularization prediction is questionable.Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.

39 keywords...

hide…