• Amer M Zeidan, Minoo Battiwalla, Deborah Berlyne, and Thomas Winkler.
• Section of Hematology, Department of Internal Medicine, Yale University, 333 Cedar Street, PO. Box 208028, New Haven, CT, 06520-8028, United States. Electronic address: amer.zeidan@yale.edu.
• Leuk. Res. 2017 Feb 1; 53: 8-12.

AbstractPatients with acquired and inherited bone marrow failure syndromes (BMFS) have ineffective hematopoiesis due to impairments of the hematopoietic stem cell compartment. Common manifestations of BMFS include varying degrees of peripheral blood cytopenias and, sometimes, progression to acute myelogenous leukemia. Research efforts have been made all over the world to improve understanding of the pathogenesis of these diseases and their clinical implications. The Aplastic Anemia and MDS International Foundation (AAMDSIF) is an independent nonprofit organization whose mission is to help patients and family members cope with BMFS. Here, we summarize recent scientific discoveries in several BMFS that were presented at the fifth International Bone Marrow Failure Disease Scientific Symposium 2016 that AAMDSIF sponsored on March 17-18, 2016, in Rockville, Maryland.Copyright © 2016 Elsevier Ltd. All rights reserved.

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