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- Gianluca Villa, Zaccaria Ricci, and Claudio Ronco.
- Section of Anaesthesiology and Intensive Care, Department of Health Science, University of Florence, Florence, Italy. Electronic address: gianlucavilla1@gmail.com.
- Crit Care Clin. 2015 Oct 1; 31 (4): 839-48.
AbstractRenal replacement therapy (RRT) is a cornerstone in the clinical management of patients with acute kidney injury. Results from different studies agree that early renal support therapy (aimed to support the residual kidney function during early phases of organ dysfunction) may reduce mortality with respect to late RRT (aimed to substitute the complete loss of function during the advanced kidney insufficiency). Although it seems plausible that a timely initiation of RRT may be associated with improved renal and nonrenal outcomes in these patients, there is scarce evidence in literature to exactly identify the most adequate onset timing for RRT.Copyright © 2015 Elsevier Inc. All rights reserved.
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