• Lasse Juel Andersen, Thomas Poulsen, Bo Krogh, and Tommy Nielsen.
• Department of Orthopaedic Surgery, Odense University Hospital, Middelfart, Denmark.
• Acta Orthop. 2007 Apr 1;78(2):187-92.

BackgroundComfort and lack of pain are important for optimal mobilization after hip replacement. We investigated the efficacy of double wound infiltration.Patients And Methods40 consecutive patients undergoing total hip replacement were randomized into two groups in this double-blinded study. They received wound infiltration at the end of surgery and through an intraarticular catheter 24 h postoperatively. The catheter was placed at the end of surgery. One group received solutions of ropivacaine, ketorolac, and adrenaline. Patients in the control group were injected with saline instead. The observation period was 6 weeks.ResultsThe patients who received the analgesic solution had less pain up to 2 weeks postoperatively. They reached an earlier and lower pain minimum during the first days postoperatively, had lower use of analgesia up to day 4 postoperatively, and were more satisfied. Use of analgesic solution resulted in less joint stiffness and better function 1 week postoperatively.InterpretationOperative and postoperative wound infiltration with multimodal drugs reduces pain and the requirement for analgesics after hip replacement, leading to faster postoperative mobilization.

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