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Multicenter Study
Reliability and clinically important improvement thresholds for osteoarthritis pain and function scales: a multicenter study.
- Jasvinder A Singh, Ruili Luo, Glenn C Landon, and Maria Suarez-Almazor.
- From the Medicine Service, Birmingham VA Medical Center and Department of Medicine, University of Alabama; Center for Surgical Medical Acute Care Research and Transitions, Birmingham VA Medical Center; Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama; Departments of Health Sciences Research and Orthopedic Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota; Section of Rheumatology and Clinical Immunology, University of Texas, M.D. Anderson Cancer Center; St. Luke's Episcopal Health System, Houston, Texas, USA.
- J Rheumatol. 2014 Mar 1; 41 (3): 509-15.
ObjectiveTo assess the reliability and clinically meaningful thresholds of intermittent and constant osteoarthritis pain (ICOAP) score, the Knee injury and Osteoarthritis Outcome Score Physical function Short-form (KOOS-PS), the Hip disability and Osteoarthritis Outcome Score Physical function Short-form (HOOS-PS), and the Quality of life subscales of HOOS/KOOS (HOOS-QOL/KOOS-QOL) in patients with knee or hip arthritis.MethodsOne hundred and ninety-five patients (141 knee, 54 hip) seen at 2 orthopedic outpatient clinics with a diagnosis of knee or hip OA completed patient-reported questionnaires (ICOAP pain scale, KOOS-PS, HOOS-PS, KOOS-QOL, HOOS-QOL) at baseline and 2-week followup. Reliability was assessed using intraclass correlation coefficients (ICC). We calculated minimum clinically important difference (MCID) and moderate improvement in the subgroup that reported change in the status of their affected joint.ResultsThe reliability as assessed by ICC was as follows: ICOAP pain scale, 0.63 (0.48, 0.74) in patients with knee arthritis, and 0.86 (0.73, 0.93) for hip arthritis; KOOS-PS, 0.66 (0.52, 0.77); HOOS-PS, 0.82 (0.66, 0.91); KOOS-QOL, 0.79 (0.69, 0.86); and HOOS-QOL, 0.67 (0.42, 0.83). MCID and moderate improvement estimates in patients with knee arthritis were ICOAP pain scale, 18.5 and 26.7; KOOS-PS, 2.2 and 15.0; and KOOS-QOL, 8.0 and 15.6. A smaller sample in patients with hip arthritis precluded MCID and moderate improvement estimates.ConclusionWe found that ICOAP pain and KOOS-PS/HOOS-PS scales were reasonably reliable in patients with hip OA. Reliability of these scales was much lower in patients with knee arthritis. Thresholds for clinically meaningful change in pain or function on these scales were estimated for patients with knee arthritis.
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