• Scand. J. Infect. Dis. · Jan 2002

    Review Case Reports

    Rat-bite fever in children: case report and review.

    • Ifeoma C Ojukwu and Cynthia Christy.
    • Strong Children's Research Center, University of Rochester School of Medicine & Dentistry, New York, USA.
    • Scand. J. Infect. Dis. 2002 Jan 1; 34 (6): 474-7.

    AbstractWe report 2 cases of rat-bite fever (RBF), a multisystem zoonosis, in children and review the literature. RBF is caused by I of 2 Gram-negative organisms: Streptobacillus moniliformis or, less commonly, Spirillum minus. Both of our cases developed in school-aged girls with a history of rat exposure who presented with a multisystem illness consisting of fever, petechial and purpuric rash, arthralgia and polyarthritis. Both responded promptly to antibiotic treatment. An additional 10 cases from a MEDLINE review (1960-2000) are reviewed. RBF must be included in the differential diagnosis of febrile patients with rashes and a history of exposure to rats.

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