• Diagn. Microbiol. Infect. Dis. · Jul 2015

    Detection of Mycoplasma genitalium from male primary urine specimens: an epidemiologic dichotomy with Trichomonas vaginalis.

    • Maureen Napierala, Erik Munson, David Wenten, Paula Phipps, Roger Gremminger, Mary Kay Schuknecht, Kimber L Munson, Vivian Boyd, Deb Hamer, Ronald F Schell, and Jeanne E Hryciuk.
    • Wheaton Franciscan Laboratory, Milwaukee, WI, USA, 53215.
    • Diagn. Microbiol. Infect. Dis. 2015 Jul 1; 82 (3): 194-8.

    AbstractA total of 2750 male urines subjected to a transcription-mediated amplification (TMA)-based Mycoplasma genitalium assay yielded 188 positive results (6.84%). This rate was similar to Chlamydia trachomatis (6.87%; P = 0.96) and greater than Neisseria gonorrhoeae (4.0%) and Trichomonas vaginalis (2.3%; P < 0.0002). Mean age of M. genitalium-infected males (30.8) was similar to N. gonorrhoeae (P = 0.78) but less than T. vaginalis (mean, 41.6; P < 0.0001). A total of 266 STI clinic encounters had at least 1 sexually transmitted infection (STI); 36.5% of these encounters had sole detection of M. genitalium (P ≤ 0.009 versus sole detection of other STI agents). In 209 community encounters with at least 1 STI, 22.0% exhibited sole detection of M. genitalium (P = 0.0007 versus sole M. genitalium detection in STI clinic males), while 18.7% had sole detection of T. vaginalis (P < 0.0002 versus detection in STI clinic males). TMA-based M. genitalium screening identifies additional cases of nongonococcal urethritis.Copyright © 2015 Elsevier Inc. All rights reserved.

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