• Seminars in oncology · Jun 2011

    Review

    Approved agents for metastatic breast cancer.

    • Monica N Fornier.
    • Breast Cancer Medicine Service, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, NY 10021, USA. fornierm@mskcc.org
    • Semin. Oncol. 2011 Jun 1; 38 Suppl 2: S3-10.

    AbstractThe US Food and Drug Administration has approved three agents for treatment of patients with metastatic breast cancer refractory to anthracyclines and taxanes: capecitabine, ixabepilone, and eribulin mesylate. There is no fixed algorithm of therapeutic choices. Median survival remains measured in months, not years. Individual patient performance status, toxicity (to past regimens and any residual toxicity), preferences, and quality of life are factors in determining optimal treatment options for metastatic breast cancer. Ongoing research is seeking to improve outcomes in this patient population.Copyright © 2011 Elsevier Inc. All rights reserved.

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