• IEEE Trans Biomed Eng · Sep 2006

    Maximum contrast beamformer for electromagnetic mapping of brain activity.

    • Yong-Sheng Chen, Chih-Yu Cheng, Jen-Chuen Hsieh, and Li-Fen Chen.
    • Department of Computer Science, National Chiao Tung University, Hsinchu, Taiwan. yschen@cs.nctu.edu.tw
    • IEEE Trans Biomed Eng. 2006 Sep 1; 53 (9): 1765-74.

    AbstractBeamforming technique can be applied to map the neuronal activities from magnetoencephalographic/electroencephalographic (MEG/EEG) recordings. One of the major difficulties of the scalar-type MEG/EEG beamformer is the determination of accurate dipole orientation, which is essential to an effective spatial filter. This paper presents a new beamforming technique which exploits a maximum contrast criterion to maximize the ratio of the neuronal activity estimated in a specified active state to the activity estimated in a control state. This criterion leads to a closed-form solution of the dipole orientation. Experiments with simulation, phantom, and finger-lifting data clearly demonstrate the effectiveness, efficiency, and accuracy of the proposed method.

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