• J Magn Reson Imaging · Jan 2021

    Review

    Quantitative Susceptibility Mapping: Technical Considerations and Clinical Applications in Neuroimaging.

    • Selvadasan Vinayagamani, R Sheelakumari, Sekar Sabarish, Santhakumar Senthilvelan, Roopa Ros, Bejoy Thomas, and Chandrasekharan Kesavadas.
    • Department of Imaging Sciences and Interventional Radiology, Trivandrum, India.
    • J Magn Reson Imaging. 2021 Jan 1; 53 (1): 23-37.

    AbstractQuantitative susceptibility mapping (QSM) is a novel magnetic resonance imaging (MRI) technique for quantifying the spatial distribution of magnetic susceptibility within an object or tissue. Recently, QSM has been widely used to study various dominant magnetic susceptibility sources in the brain, including iron and calcium. In addition, the method enables mapping of the cerebral metabolic rate of oxygen, which could act as a new metabolic biomarker for diseases that involve disruption of the brain's oxygen supply. Thus, the clinical applications of QSM are wide-reaching and hold great promise as imaging biomarkers for studying several neurological diseases. This review aims to summarize the physical concepts and potential clinical applications of QSM in neuroimaging. EVIDENCE LEVEL: 5 TECHNICAL EFFICACY: Stage 2.© 2020 International Society for Magnetic Resonance in Medicine.

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