• Francesco S Violante, Maurizio Zompatori, Piero Lovreglio, Pietro Apostoli, Francesco Marinelli, and Roberta Bonfiglioli.
• Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy francesco.violante@unibo.it.
• BMJ Open. 2019 Sep 18; 9 (9): e029657.

ObjectiveConflicting evidence exists to what extent manual material handling (MMH) causes lumbar disc disease, lack of evidence exist that this effect takes place especially at L5-S1 level, where the greatest moment occurs. The aim was to assess if lumbar vertebral body and disc changes are more common in people whose job involves significant MMH and, if so, to evaluate if lumbar vertebral body and disc changes are more prevalent in the lower part of the lumbar spine (L4-L5 and L5-S1).DesignObservational, cross-sectional, with quasi-random recruitment.SettingOutpatient radiology units of three large hospitals in northern (Bologna and Brescia) and southern (Bari) Italy.Participants183 consecutive adult subjects (89 males, 94 females) aged 20-70 years referred by the general practitioner or a specialist for MRI of the lumbar spine.Primary And Secondary Outcome MeasuresNeuroradiologists (blind to clinical assessment) evaluated the prevalence of intervertebral disc and vertebral body changes in standardised MRI examinations. History of personal and family musculoskeletal diseases and injuries, current and previous MMH at work and during leisure time were assessed by interview and self-administered questionnaire.ResultsParticipants were classified according their occupational exposure to MMH. No association was found between MMH and vertebral body and intervertebral disc changes, whereas age over 45 years was consistently associated with more disc extension beyond the interspace changes, Pfirrmann changes, osteophytes and Modic changes: the association was statistically significant at the conventional 5% level.ConclusionsAge, and not MMH, seems to primarily affect the presence of intervertebral disc changes; prospective studies are needed to better explore the relationship between MMH and the possible presence (and level) of lumbar vertebral body and/or disc changes.© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

46 keywords...

hide…