• Pierrick Coupé, José V Manjón, Elias Gedamu, Douglas Arnold, Montserrat Robles, and D Louis Collins.
• McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University 3801, University Street, Montreal, Canada H3A 2B4. pierrick.coupe@gmail.com
• Med Image Anal. 2010 Aug 1; 14 (4): 483-93.

AbstractIn this paper, a new object-based method to estimate noise in magnitude MR images is proposed. The main advantage of this object-based method is its robustness to background artefacts such as ghosting. The proposed method is based on the adaptation of the Median Absolute Deviation (MAD) estimator in the wavelet domain for Rician noise. The MAD is a robust and efficient estimator initially proposed to estimate Gaussian noise. In this work, the adaptation of MAD operator for Rician noise is performed by using only the wavelet coefficients corresponding to the object and by correcting the estimation with an iterative scheme based on the SNR of the image. During the evaluation, a comparison of the proposed method with several state-of-the-art methods is performed. A quantitative validation on synthetic phantom with and without artefacts is presented. A new validation framework is proposed to perform quantitative validation on real data. The impact of the accuracy of noise estimation on the performance of a denoising filter is also studied. The results obtained on synthetic images show the accuracy and the robustness of the proposed method. Within the validation on real data, the proposed method obtained very competitive results compared to the methods under study.Copyright 2010 Elsevier B.V. All rights reserved.

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