• Pascale R Salameh and Bernadette Abi Saleh.
• Faculty of Pharmacy, Lebanese University, Lebanon. pascalesalameh@yahoo.com
• J Med Liban. 2004 Apr 1; 52 (2): 64-70.

AbstractPesticides are known for their toxicity and are still widely used, especially in agriculture. Increasing attention is being focused on the health effects affecting humans occupationally exposed to pesticides, particularly agricultural workers. The objective of this study was to assess the association between occupational exposure to pesticides with recurrent symptoms and acute intoxications, in comparison with other workers in Lebanon. A cross-sectional study was undertaken, where a standardized questionnaire was administered to 89 exposed and 88 non exposed workers. Subjects exposed to pesticides reported more upper respiratory tract infections (PR = 9.39 ; p < 10(-4)), anorexia (PR = 3.63 ; p = 0.03), epistaxis (PR = 2.97; p = 0.02), immunoallergic (PR = 1.58 ; p = 0.01) and gastrointestinal (PR = 2.13 ; p < 10(-4)) symptoms. Acute pesticide intoxications requiring hospitalization were also more common (PR = 4.26; p = 0.01). Adjustment over potential confounding did not change the results, except for the appearance of an association of central (PR = 1.50 ; p = 0.04) and autonomic nervous systems symptoms (PR = 3.92 ; p = 0.01) with agricultural work in Mount Lebanon. Our results suggest that agricultural workers have a higher prevalence of multiple symptoms, which may be due to subacute intoxications by pesticides that did not need hospitalization. In addition, these workers have a higher risk of having an acute intoxication due to pesticides, exposing them to life-threatening situations.

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