• Biull Eksp Biol Med · Dec 1982

    Comparative Study

    [Ultrastructural changes in the hepatic mast and plasma cells of pregnant rats with endotoxic shock].

    • O V Nikulin, B A Saakov, and E A Bardakhch'ian.
    • Biull Eksp Biol Med. 1982 Dec 1; 94 (12): 107-10.

    AbstractUltrastructural alterations in mast and plasma cells of pregnant rat liver were studied in the initial period of endotoxin shock. A significant increase in functional activity of mast and plasma cells and the presence of intercellular contacts and contacts with cells of perisinusoidal space were found. The data obtained suggest that endotoxin stimulates connective tissue cells, leading to the release of mediators and biologically active substances responsible for hepatic injury during endotoxemia.

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