• La Revue du praticien · Feb 2007

    Review Comparative Study

    [Management of localized germ-cell tumours of the testis].

    • Yohann Loriot and Karim Fizazi.
    • Département de médecine, institut Gustave-Roussy, Villejuif Cedex.
    • Rev Prat. 2007 Feb 28; 57 (4): 379-84.

    AbstractStage 1 is currently the most frequent pattern at diagnosis of germ-cell tumours. Prognosis is excellent and different options are available after orchidectomy. The therapeutic choice should be taken after fair and extensive information regarding the limitations of each option therefore taking into account both predictive factors of relapse and patient individual willing. In case of pure seminoma, prophylactic radiotherapy directed to the retroperitoneal lymph nodes, chemotherapy by single-agent carboplatin and surveillance with differed treatment at relapse are the three currently available attitudes. In non-seminomatous germ cell tumours three options should also be considered: surveillance (watchful waiting), chemotherapy by two cycles of BEP, or retroperitoneal lymph node dissection.

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