• Gan To Kagaku Ryoho · Aug 1997

    Meta Analysis

    [Benefits of adjuvant chemotherapy for breast cancer].

    • K Motomura, S Noguchi, H Inaji, and H Koyama.
    • Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan.
    • Gan To Kagaku Ryoho. 1997 Aug 1; 24 (10): 1239-44.

    AbstractThe main therapy for primary breast cancer is not surgery, but a systemic therapy involving administration of cytotoxic chemotherapy or the use of ablative or additive endocrine therapy to control disseminated micrometastasis. The results of randomized trials and meta-analysis show that CMF, the standard adjuvant chemotherapy, is effective regardless of axillar lymph node involvement or menopausal status. Effectiveness of adjuvant chemotherapy with an anthracyclin-based regimen remains controversial. The trial by CUBC and NSAS-BC comparing UFT, widely used in the management of patients with breast cancer in Japan, with CMF is on-going.

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