• Ugeskrift for laeger · Mar 1999

    Randomized Controlled Trial Clinical Trial

    [The effect of pedicle screw instrumentation on posterolateral spinal fusion. A prospective, randomized study with a two-year follow-up].

    • F B Christensen, K Thomsen, S P Eiskjaer, E S Hansen, S Fruensgaard, J Gelinick, and C E Bünger.
    • Ortopaedkirurgisk afdeling E, Arhus Universitetshospital, Arhus Kommunehospital. fbc@dadlnet.dk
    • Ugeskr. Laeg. 1999 Mar 29; 161 (13): 1920-5.

    AbstractThe aim was to evaluate the effect of supplementary pedicle screw fixation (Cotrel-Dubousset [CD]) in posterolateral lumbar spinal fusion. The study comprises 130 patients undergoing lumbar or lumbosacral fusion for spondyloisthesis grades I-II or degenerative segmental instability conditions. The patients were randomly allocated for no instrumentation (n = 66) or CD instrumentation (n = 64) in posterolateral lumbar fusion. A 97.7% follow-up was achieved. There were no significant differences between the two groups concerning fusion rates assessed by X-ray or functional outcomes assessed by Dallas Pain Questionnaire. The global patient satisfaction was 82% in the instrumented group versus 74% in the noninstrumented group. Instrumentation increased both operation time, blood loss, and early re-operation rates significantly. A high patient satisfaction was found in both groups. However, the results from this study do not justify the general use of pedicle screw fixation alone as an adjunct to posterolateral lumbar fusion.

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