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Neuroimaging Clin. N. Am. · Aug 2021
ReviewPreoperative Molecular Testing of Thyroid Nodules: Current Concepts.
- Michelle D Williams.
- Department of Pathology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 085, Houston, TX 77030, USA. Electronic address: mdwillia@mdanderson.org.
- Neuroimaging Clin. N. Am. 2021 Aug 1; 31 (3): 301-312.
AbstractRobust molecular testing is commercially available for adjuvant assessment of cytologically indeterminate thyroid nodules. Testing has been developed and optimized for fine needle aspiration biopsy collections of thyroid nodules typically under ultrasound evaluation. These assays use a combination of gene expression and/or DNA and RNA assessments for molecular alterations to stratify indeterminate thyroid nodules as benign with risk level similar to benign cytologic read or suspicious with increased risk of malignancy. Guidelines for when to consider adjuvant molecular testing will be discussed.Copyright © 2021 Elsevier Inc. All rights reserved.
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