• Anna Binetti, Martina Mosing, Muriel Sacks, Luc Duchateau, Frank Gasthuys, and Stijn Schauvliege.
• Department of Large Animals Surgery and Anaesthesia, Ghent University, Gent, Belgium. Electronic address: anna.binetti@Ugent.be.
• Vet Anaesth Analg. 2018 Nov 1; 45 (6): 760-771.

ObjectiveTo describe the cardiorespiratory effects of a change in table position in anaesthetized horses.Study DesignProspective, crossover, randomized, experimental study.AnimalsSix adult horses (mean body weight 621 ± 59 kg, aged 13 ± 4 years).MethodsThe horses were anaesthetized twice in dorsal recumbency. They were either placed in the Trendelenburg position (head down; HD) followed by reverse Trendelenburg position (head up; HU) or in reverse order. Every position was maintained for 90 minutes. The order of positions was randomly assigned at initial anaesthesia. Extensive cardiorespiratory monitoring was performed. Statistical analysis consisted of a mixed model with horses as random effect and time, position, section of anaesthesia and interaction between those as fixed effects (p < 0.05).ResultsWhen HU was applied during the first section of anaesthesia, PaO2, (p = 0.012), oxygen saturation (SaO2, p < 0.01) and oxygen content (CaO2, p < 0.01) were significantly higher, while venous admixture (Q˙s/Q˙t, p < 0.01), mean arterial (p = 0.039), right atrial (p < 0.01) and mean pulmonary arterial pressure (p < 0.01) were lower than in HD. After changing from HU to HD, PaO2 and SaO2 remained higher and Q˙s/Q˙t lower compared to the inverse order. Independent of the order, in the HD position Q˙s/Q˙t (p = 0.019) increased while PaO2 (p < 0.01), SaO2 (p = 0.011), CaO2 (p < 0.01), venous PO2 (Pv¯O2; p = 0.019), venous saturation (p = 0.004) and venous oxygen content (p = 0.010) decreased over time. No significant differences were found for cardiac output, oxygen delivery, oxygen consumption and dobutamine requirement between the two positions.Conclusions And Clinical RelevanceGas exchange is better preserved in HU compared to HD, especially if applied from the start of the anaesthesia.Copyright © 2018 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

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