• Environmental pollution · Mar 2019

    Fine particulate matter exposure and medication dispensing during and after a coal mine fire: A time series analysis from the Hazelwood Health Study.

    • Amanda L Johnson, Joanna F Dipnall, Martine Dennekamp, Grant J Williamson, Caroline X Gao, Matthew T C Carroll, Christina Dimitriadis, Jillian F Ikin, Fay H Johnston, Alexander C McFarlane, Malcolm R Sim, Dion A Stub, Michael J Abramson, and Yuming Guo.
    • Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Level 2, 553 St Kilda Road, Melbourne, Victoria, 3004, Australia.
    • Environ. Pollut. 2019 Mar 1; 246: 1027-1035.

    AbstractLimited research has examined the impacts of coal mine fire smoke on human health. The aim of this study was to assess the association between prolonged smoke PM2.5 exposure from a brown coal mine fire that burned over a seven week period in 2014 and medications dispensed across five localities in South-eastern Victoria, Australia. Spatially resolved PM2.5 concentrations were retrospectively estimated using a dispersion model coupled with a chemical transport model. Data on medications dispensed were collected from the national Pharmaceutical Benefits Schedule database for 2013-2016. Poisson distributed lag time series analysis was used to examine associations between daily mine fire-related PM2.5 concentrations and daily counts of medications dispensed for respiratory, cardiovascular or psychiatric conditions. Factors controlled for included: seasonality, long-term trend, day of the week, maximum ambient temperature and public holidays. Positive associations were found between mine fire-related PM2.5 and increased risks of medications dispensed for respiratory, cardiovascular and psychiatric conditions, over a lag range of 3-7 days. A 10 μg/m3 increase in coal mine fire-related PM2.5 was associated with a 25% (95%CI 19-32%) increase in respiratory medications, a 10% (95%CI 7-13%) increase in cardiovascular medications and a 12% (95%CI 8-16%) increase in psychiatric medications dispensed. These findings have the potential to better prepare for and develop more appropriate public health responses in the event of future coal mine fires.Copyright © 2019 Elsevier Ltd. All rights reserved.

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