• Pain · Mar 1984

    Comparative Study

    The safety and efficacy of intrathecal diamorphine.

    • David W Barron and John E Strong.
    • Withers Orthopaedic Centre, Musgrave Park Hospital, Belfast BT9 7JB UK 4 Riverside, Church Road, Holywood BT17 9DB United Kingdom.
    • Pain. 1984 Mar 1; 18 (3): 279-285.

    AbstractOne hundred and seventy-eight patients undergoing total hip replacement and 67 patients undergoing spinal surgery were given diamorphine intrathecally in varying doses. Doses in mg/kg were plotted against duration of analgesia and the absence of retention and emetic symptoms in each type of surgery. Analysis showed that these were not dose dependent within the therapeutic range of 0.005-0.015 mg/kg.

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