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- T Cerny and C Meier.
- Institut für Medizinische Onkologie, Universität Bern, Inselspital.
- Swiss Med Wkly. 1989 Aug 26; 119 (34): 1137-47.
AbstractNeurotoxicity is of increasing importance in the treatment of cancer patients. Since the dose-limiting hematological toxicity of most cytostatic drugs can now be overcome by modern supportive therapy, high-dose chemotherapy with curative intent can be used more often. Non-hematological toxicities such as neurotoxicity will therefore become dose-limiting with greater frequency, and to avoid disabling neurological side effects of chemotherapy the drug-induced neurological disturbances must be recognized before irreversible damage has occurred. The neurological side effects of the cytostatic drugs are reviewed.
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