• Recent Results Cancer Res. · Jan 1985

    Surgical intervention and metastasis.

    • R Keller.
    • Recent Results Cancer Res. 1985 Jan 1; 98: 11-6.

    AbstractRecent findings, briefly summarized here, show that the dissemination of neoplastic cells is an early and continuing process; that individual tumor cells in a malignant tumor possess differing metastatic capacities; and that metastases can arise from specific subpopulations of tumor cells. These findings have considerable implications for the understanding and treatment of systemic malignancies. The underlying cause for the finding that surgical removal of the primary local tumor is often followed by considerably enhanced outgrowth of established micrometastases is not yet understood. The trauma and stress associated with surgical intervention does not of itself seem to constitute a major tumor-promoting component. More likely candidates responsible for enhanced outgrowth of metastases after surgery are the removal of the growth-inhibitory restraint that the primary tumor exerts on disseminated neoplastic cells.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…