• J Natl Med Assoc · Jun 2021

    Case Reports

    It's the Bloody Gallbladder! Spontaneous Gallbladder Hemorrhage Following Factor Xa Inhibition.

    • Mohammad Umair Azam, Muaz A Ibrahim, Isaac Perry, Steven B Ellison, Amanda Barrett, and Kenneth J Vega.
    • Department of Medicine, Augusta University-Medical College of Georgia, Augusta, GA, USA.
    • J Natl Med Assoc. 2021 Jun 1; 113 (3): 252-254.

    AbstractSpontaneous gallbladder hemorrhage (SGBH) is a rare diagnosis related to trauma, malignancy or vascular abnormalities, associated with significant morbidity and mortality. We present a case of SGBH in a 55-year-old patient with right upper quadrant (RUQ) pain following initiation of apixaban for deep vein thrombosis post recent kidney transplant. Multiple imaging studies revealed a distended gallbladder with heterogeneous hyperdense material in the lumen and cystic duct obstruction. Surgery revealed a gallbladder with chronic cholecystitis, hemorrhage and hematoma. This case highlights a rare adverse event of anticoagulation, and SGBH should be considered when acute RUQ pain occurs in this setting.Copyright © 2020 National Medical Association. Published by Elsevier Inc. All rights reserved.

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