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J Clin Monit Comput · Feb 2022
ReviewQuestions about COVID-19 associated coagulopathy: possible answers from the viscoelastic tests.
- Vittorio Pavoni, Lara Gianesello, Maddalena Pazzi, Pietro Dattolo, and Domenico Prisco.
- Emergency Department and Critical Care Area, Anesthesia and Intensive Care Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, Italy.
- J Clin Monit Comput. 2022 Feb 1; 36 (1): 556955-69.
AbstractAbnormal coagulation parameters are often observed in patients with coronavirus disease 2019 (COVID-19) and the severity of derangement has been associated with a poor prognosis. The COVID-19 associated coagulopathy (CAC) displays unique features that include a high risk of developing thromboembolic complications. Viscoelastic tests (VETs), such as thromboelastometry (ROTEM), thromboelastography (TEG) and Quantra Hemostasis Analyzer (Quantra), provide "dynamic" data on clot formation and dissolution; they are used in different critical care settings, both in hemorrhagic and in thrombotic conditions. In patients with severe COVID-19 infection VETs can supply to clinicians more information about the CAC, identifying the presence of hypercoagulable and hypofibrinolysis states. In the last year, many studies have proposed to explain the underlying characteristics of CAC; however, there remain many unanswered questions. We tried to address some of the important queries about CAC through VETs analysis.© 2021. The Author(s), under exclusive licence to Springer Nature B.V.
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