• J Clin Sleep Med · Aug 2010

    Case Reports

    Topiramate responsive exploding head syndrome.

    • Gaurang M Palikh and Bradley V Vaughn.
    • Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7025, USA. patelg@neurology.unc.edu
    • J Clin Sleep Med. 2010 Aug 15; 6 (4): 382-3.

    AbstractExploding head syndrome is a rare phenomenon but can be a significant disruption to quality of life. We describe a 39-year-old female with symptoms of a loud bang and buzz at sleep onset for 3 years. EEG monitoring confirmed these events occurred in transition from stage 1 sleep. This patient reported improvement in intensity of events with topiramate medication. Based on these results, topiramate may be an alternative method to reduce the intensity of events in exploding head syndrome.

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