• BMJ case reports · Dec 2020

    Case Reports

    Delayed urticaria or anaphylaxis after consumption of red meat with evidence of alpha-gal sensitisation.

    • Maria Beatriz Garcia, Andres F Gomez-Samper, Elizabeth Garcia, and Augusto Peñaranda.
    • Allergology Service, Fundacion Santa Fé de Bogotá, Bogotá, Colombia marabagarcia@yahoo.com.
    • BMJ Case Rep. 2020 Dec 28; 13 (12).

    AbstractFood allergies to red meat, specifically to galactose-alpha-1,3-galactose (alpha-gal), a mammalian oligosaccharide, are considered to be very rare, especially in Asia and Latin America. Most of the cases reported are characterised by symptoms of delayed urticaria or anaphylaxis after the consumption of red meat. Sensitisation to red meat has been linked to the use of cetuximab or tick bites, especially from the Amblyomma americanum and Ixodes spp species. Here, we documented a case study from a Colombian male patient with symptoms of delayed urticaria and anaphylaxis with a history of tick bites in Colombia. The patient presented with IgE antibodies specific to alpha-gal, which is the most common epitope linked to red meat allergy induced by tick bites.© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

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