• Joshua Bucher and Alex Koyfman.
• Rutgers - Robert Wood Johnson Medical School, Piscataway, New Jersey.
• J Emerg Med. 2015 Dec 1; 49 (6): 920-7.

BackgroundIntubation of the neurologically injured patient is a critical procedure that must be done in a manner to prevent further neurologic injury. Although many different medications and techniques have been used to meet specific needs, there is little to no evidence to support many claims.ObjectiveTo review the literature regarding important topics relating to intubating patients with neurologic injury.DiscussionAirway management requires ideal preoxygenation and airway maneuvers to minimize manipulation of the larynx and to maximize first-pass success. There is no evidence that lidocaine pretreatment decreases intracerebral pressure (ICP). Fentanyl can be used to help blunt the hemodynamic response to intubation. Esmolol is another medication that can blunt the hemodynamic response. Ketamine can be used and is possibly the ideal agent, having a neutral hemodynamic profile. A prefasciculation dose for neuromuscular blockade has not been shown to have any effect on ICP.ConclusionsIdeal intubation conditions should be obtained through the use of airway manipulation techniques and appropriate medication choice for rapid sequence intubation in patients who are neurologically injured.Copyright © 2015 Elsevier Inc. All rights reserved.

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