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Anesthesia and analgesia · Dec 2009
The efficacy and safety of continuous intravenous administration of remifentanil for birth pain relief: an open study of 205 parturients.
- Paola D'Onofrio, Anna Maria Melani Novelli, Federico Mecacci, and Gianfranco Scarselli.
- SOD Anestesia DAI Materno-Infantile, AOU Careggi, Viale Pieraccini 17, Firenze, Italia. paodono@libero.it
- Anesth. Analg. 2009 Dec 1;109(6):1922-4.
AbstractIn an observational study, we prospectively evaluated the efficacy and safety of remifentanil in 205 parturients. Remifentanil was administered as a continuous infusion. The initial infusion of 0.025 microg x kg(-1) x min(-1) was increased in a stepwise manner to a maximum dose of 0.15 microg x kg(-1) x min(-1). Maternal pain, other maternal and fetal variables, side effects, and satisfaction were recorded. The mean (+/-sd) visual analog score before the start of the infusion was 9.4 +/- 1.2 cm and decreased to 5.1 +/- 0.4 cm after 5 min and 3.6 +/- 1.5 cm after 30 min. The maternal side effects were minimal and no fetal or neonatal side effects were noted.
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