• Ugeskrift for laeger · Sep 2007

    [Adjuvant treatment of breast cancer. Endocrine therapy].

    • Henning T Mouridsen and Jørn Andersen.
    • Rigshospitalet, Finsencentret, Onkologisk Klinisk 5074, København Ø. henning.mouridsen@rh.hosp.dk
    • Ugeskr. Laeg. 2007 Sep 10; 169 (37): 3072-6.

    AbstractFor women with steroid receptor-positive breast cancers, endocrine therapy has proven to be a major component of adjuvant therapy reducing the risk of recurrence and death. The selective estrogen-receptor modulator (SERM) tamoxifen has been well established as safe and effective in the adjuvant care of both pre- and postmenopausal women. For premenopausal women, ovarian suppression is an important option to be considered. Additionally, aromatase inhibitors have recently demonstrated further benefits in postmenopausal women. The ideal sequencing of treatment with tamoxifen and/or an aromatase inhibitor is the subject of several ongoing studies.

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