• Kotaro Shimada, Hiroyoshi Isoda, Tomohisa Okada, Yoji Maetani, Shigeki Arizono, Yuusuke Hirokawa, Toshikazu Kamae, and Kaori Togashi.
• Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. kotaro@kuhp.kyoto-u.ac.j
• Eur J Radiol. 2009 Apr 1; 70 (1): 111-7.

ObjectiveTo selectively visualize the hepatic arteries using the respiratory-triggered three-dimensional (3D) true steady-state free-precession (SSFP) projection magnetic resonance angiographic sequence with time spatial labeling inversion pulse (T-SLIP), and describe the optimization of this protocol.Materials And MethodsTwenty healthy volunteers were examined in this study. A respiratory-triggered 3D true SSFP combined with T-SLIP was performed. Among several key factors that affect the image quality, the most important is the inversion time (TI). Therefore, according to the difference in TI, four image groups: group A (TI of 800 ms), group B (TI of 1000 ms), group C (TI of 1200 ms), and group D (TI of 1400 ms), were assigned and compared to detect the optimal TI for hepatic artery visualization. For quantitative assessment, the relative signal intensity, i.e., Cv-l (vessel-to-liver contrast) of the right hepatic artery was measured. For qualitative evaluation, the quality of vessel visualization and the order of identified hepatic artery branches were evaluated by two radiologists.ResultsSelective and high-contrast visualization of the hepatic arteries was acquired in all cases. Regarding the quantitative assessment, Cv-l decreased in group D due to background signal recovery, but there was no significant difference between groups (p-value >0.05). Regarding the qualitative evaluation, there were significant differences between group A and the other groups (p-value <0.01) and between groups B and C (p-value <0.05). In group C, both the image quality score and mean value for the order of the hepatic artery branches were highest, and a TI of 1200 ms was thought to be optimal regarding the balance between vessel-to-liver contrast and peripheral hepatic artery visualization.ConclusionThe MR angiographic technique using true SSFP with T-SLIP enabled the selective visualization of hepatic arteries without the need for an exogenous contrast agent or breath-hold.

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