• American heart journal · Aug 2020

    Multicenter Study Comparative Study

    Discontinuation rates of warfarin versus direct acting oral anticoagulants in US clinical practice: Results from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II).

    • Larry R Jackson, Sunghee Kim, Rosalia Blanco, Laine Thomas, Jack Ansell, Gregg C Fonarow, Bernard J Gersh, Alan S Go, Peter R Kowey, Kenneth W Mahaffey, Elaine M Hylek, Eric D Peterson, Jonathan P Piccini, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II.
    • Duke Clinical Research Institute, Duke University Medical Center, Durham, NC. Electronic address: larry.jackson@dm.duke.edu.
    • Am. Heart J. 2020 Aug 1; 226: 85-93.

    AbstractWhile oral anticoagulation is a cornerstone of stroke prevention therapy in atrial fibrillation (AF), few studies have evaluated comparative discontinuation rates in clinical practice. The objective of this study is to evaluate discontinuation rates among patients on warfarin and direct oral anticoagulants (DOACs) in clinical practice.Copyright © 2020 Elsevier Inc. All rights reserved.

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