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Case Reports
Intravenous lacosamide--an effective add-on treatment of refractory status epilepticus.
- Johannes Michael Albers, Gabriel Möddel, Ralf Dittrich, Corinna Steidl, Sonja Suntrup, Erich Bernd Ringelstein, and Rainer Dziewas.
- Department of Neurology, University Hospital Muenster, Germany. albersjo@uni-muenster.de
- Seizure. 2011 Jun 1; 20 (5): 428-30.
AbstractStatus epilepticus (SE) is a frequent neurological emergency requiring immediate treatment. Therapy usually requires intravenous anticonvulsive medication. Lacosamide is a novel anticonvulsant drug that is available as infusion solution. We describe seven patients with focal SE who were treated with intravenous Lacosamide. All patients in our case series were unsuccessfully treated with other antiepileptic drugs before Lacosamide i.v. was added. In all cases, SE was terminated within 24 h after Lacosamide. There were no serious side effects or adverse events attributable to Lacosamide i.v. Our data suggest that Lacosamide might be an effective add-on treatment, if standard drugs fail or are unsuitable.Copyright © 2011 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
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